Week 1 Start/Sit Advice — 2026 NFL Season

Fantasy Draft Pros has your complete Week 1 start/sit advice for the 2026 NFL season. Updated with the latest injury reports, depth chart changes, and matchup analysis.

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Week 1 Key Injury Updates

Ashton Jeanty (RB, LV) — Sprained ankle, questionable. HC Kubiak optimistic he plays vs. MIA.
Tank Dell (WR, HOU) — Placed on IR with return designation. Out at least 4 games.
Rome Odunze (WR, CHI) — Exited practice with injury. Monitor Friday report.
D'Andre Swift (RB, CHI) — Exited practice with injury. Status unclear.
Patrick Mahomes (QB, KC) — Fully cleared from ACL. Starting Monday Night vs. DEN.
Jeremiyah Love (RB, ARI) — High ankle sprain, 50/50 for Week 1 vs. LAC.

Week 1 Must-Starts

Jaxon Smith-Njigba (SEA vs. NE — season opener), Nico Collins (HOU — massive target share with Dell on IR), MarShawn Lloyd (GB — lead back with Jacobs on exempt list), Drake Maye (NE — high-scoring opener projected).

Week 1 Sleepers

Tyler Allgeier (ARI — if Love sits), Zamir White (LV — if Jeanty sits), De'Zhaun Stribling (SF — WR2 with Pearsall out for season), Kaleb Johnson (GB — committee upside).

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